Poolbeg Pharma PLC
06 October 2026
Poolbeg Pharma plc
Cancer Immunotherapy-Induced CRS Patent Granted in South Korea
Patent grant further strengthens POLB 001’s global intellectual property portfolio
6 October 2026 -Poolbeg Pharma(AIM: POLB, 'Poolbeg' or the 'Company'),a clinical-stage biopharmaceutical company with a core focus on transforming the cancer immunotherapy field, announces that a South Korean patent relating to POLB 001 has been formally granted. The patent, entitled "Medicinal products and methods for the alleviation of cancer immunotherapy-associated cytokine release syndrome", provides protection for POLB 001 and the use of any p38 MAP kinase inhibitor for the prevention of cancer immunotherapy-associated Cytokine Release Syndrome ("CRS") in South Korea with a default expiry of 2044.
POLB 001 is a potent and selective p38 MAP kinase inhibitor being developed as a potential preventative treatment for cancer immunotherapy-associated CRS. CRS is a recognised and potentially serious complication associated with a range of cancer immunotherapies and represents a significant unmet medical need.
The South Korean patent grant further strengthens Poolbeg's growing international intellectual property portfolio for POLB 001, particularly in the strategically important area of cancer immunotherapy-associated CRS. Poolbeg has continued to expand its patent estate around POLB 001 through granted patents, including Europe, Canada and Australia, and patent applications covering multiple therapeutic applications and territories. Developing a robust global intellectual property portfolio remains a key priority for the Company, enhancing POLB 001's value and attractiveness to prospective pharmaceutical partners.
Jeremy Skillington, PhD, Chief Executive Officer of Poolbeg Pharma, said:"This latest patent grant for South Korea adds to our growing international cancer immunotherapy-associated CRS patent estate, enhancing POLB 001's attractiveness to prospective partners, and reflects the continued momentum we are generating across the programme.”
Enquiries
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Poolbeg Pharma Plc Jeremy Skillington, CEO Ian O'Connell, CFO
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+44 (0) 207 183 1499 |
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CavendishCapital Markets Ltd(NOMAD & Joint Broker) Geoff Nash, Trisyia Jamaludin(Corporate Finance) Nigel Birks (Life Science Specialist Sales) Harriet Ward(ECM) |
+44 (0) 207 220 0500 |
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Shore Capital Stockbrokers Ltd(Joint Broker)
David Coaten, Harry Davies-Ball (Corporate Advisory)
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+44 (0) 207 408 4090 |
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J&E Davy(Joint Broker) Anthony Farrell,Niall Gilchrist
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+353 (0) 1 679 6363 |
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Optimum Strategic Communications Nick Bastin,Katie Flint, Henry Williams
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+44 (0) 208 078 4357 |
About Poolbeg Pharma plc
Poolbeg Pharmaplc(AIM: POLB) is a clinical-stage biopharmaceuticalcompany with a core focus on transforming the cancer immunotherapy field. The Company’s lead asset, POLB 001, has the potential to expand administration of cancer immunotherapies from centralised specialist cancer centres into community hospitals by making the treatments safer through the prevention of the life-threatening side effect, Cytokine Release Syndrome (CRS).As such, POLB 001 could increase the number of patients that can receive these life-saving treatments, thereby increasing the market opportunity. Poolbeg is also advancing the development of a patient-friendly therapy for obesity with an oral encapsulated GLP-1, offering a differentiated approach within one of the world’s largest markets. With multiple near-term clinical value inflection points, and an experienced team with a proven track record, Poolbeg is focussed on partnering its high value programmes that are targeting large markets and addressing critical unmet medical needs.
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